Event Title

Mechanisms Through Which Repo and PntP1 Determine Longitudinal Glial Cell Fate

Faculty Advisor

Pavithra Vivekanand

Start Date

25-4-2017 12:00 PM

End Date

25-4-2017 1:00 PM

Description

Lateral glial cell differentiation in Drosophila melanogaster is regulated by the master gene glial cells missing (gcm). Downstream transcriptional activators, Repo and PntP1, promote glial cell fate in longitudinal glial cells, a subtype of lateral glia. Immunostaining in homozygous pnt mutants showed abnormal longitudinal glia development. Immunostaining in repo mutants was used to determine if Repo activates transcription of nazgul (cg31235), a gene that is expressed in longitudinal glial cells but not other lateral glial cells. Repo mutants showed reduced nazgul expression, which indicates that Repo activates the transcription of nazgul. ​

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Apr 25th, 12:00 PM Apr 25th, 1:00 PM

Mechanisms Through Which Repo and PntP1 Determine Longitudinal Glial Cell Fate

Lateral glial cell differentiation in Drosophila melanogaster is regulated by the master gene glial cells missing (gcm). Downstream transcriptional activators, Repo and PntP1, promote glial cell fate in longitudinal glial cells, a subtype of lateral glia. Immunostaining in homozygous pnt mutants showed abnormal longitudinal glia development. Immunostaining in repo mutants was used to determine if Repo activates transcription of nazgul (cg31235), a gene that is expressed in longitudinal glial cells but not other lateral glial cells. Repo mutants showed reduced nazgul expression, which indicates that Repo activates the transcription of nazgul. ​