Event Title

Photocatalytic Degradation Rates of Warfarin placed in Sodium Hydroxide and a UV Reactor

Faculty Advisor

Dr. Lou ann Tom

Start Date

23-4-2019 12:00 PM

End Date

23-4-2019 1:00 PM

Description

Photocatalytic degradation of pharmaceuticals is being used to determine if a practical method of disposal is a useful alternative to expensive incineration. Disposal of unused drugs is usually done in the household garbage, which can lead negative impacts on the environment or to people due to misuse and abuse. Photocatalytic degradation of pharmaceuticals is a promising alternative for proper disposal. Photocatalytic degradation of (RS)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one (warfarin) was evaluated. Warfarin was initially left alone to see how to would degrade over time and then was also placed in sodium hydroxide (NaOH). All degradation rates were compared with a control with no UV exposure. High Performance Liquid Chromatography (HPLC) was used to analyze the drug remaining in the solutions over time. Initial results indicate that degradation with UV light and no acid show that there is not much decay over time, the results of the degradation with NaOH and the UV light show that warfarin is degrading over time in the NaOH solution and with the UV light.

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Apr 23rd, 12:00 PM Apr 23rd, 1:00 PM

Photocatalytic Degradation Rates of Warfarin placed in Sodium Hydroxide and a UV Reactor

Photocatalytic degradation of pharmaceuticals is being used to determine if a practical method of disposal is a useful alternative to expensive incineration. Disposal of unused drugs is usually done in the household garbage, which can lead negative impacts on the environment or to people due to misuse and abuse. Photocatalytic degradation of pharmaceuticals is a promising alternative for proper disposal. Photocatalytic degradation of (RS)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one (warfarin) was evaluated. Warfarin was initially left alone to see how to would degrade over time and then was also placed in sodium hydroxide (NaOH). All degradation rates were compared with a control with no UV exposure. High Performance Liquid Chromatography (HPLC) was used to analyze the drug remaining in the solutions over time. Initial results indicate that degradation with UV light and no acid show that there is not much decay over time, the results of the degradation with NaOH and the UV light show that warfarin is degrading over time in the NaOH solution and with the UV light.